Apicha Community Health's LGBTQ+ Center in New York, founded in 1989, provides culturally competent comprehensive medical and mental health care and supportive services, including HIV specialty care, transgender primary care, sexual and behavioral health services, and community education programs.

A global leader in LGBTQ healthcare for over 50 years, Callen-Lorde Community Health Center in New York provides sensitive, quality health care and related services to the LGBTQ, regardless of ability to pay.

Destination Tomorrow strives to economically empower the LGBTQ community of the South Bronx, providing a safe space to grow and flourish with in-house and community programs that offer education, health, and practical life skills.

Serving LGBTQ youth ages 13-24 and their families, Hetrick-Martin is the oldest and largest organization in the US offering services to LGBTQ youth. Hetrick-Martin is a model organization, offering innovative programs that foster healthy development and a safe supportive environment addressing healthcare, homelessness, education, economic empowerment, mental health, and more.

The largest and oldest organization in the U.S. dedicated to improving the lives of LGBT elders, SAGE, headquartered in New York City, offers supportive services and consumer resources to LGBT older people and their caregivers nationwide.

Committed to empowering and saving the lives of LGBTQ youth from homelessness since 2002, the Ali Forney Center provides food, shelter, medical care, and innovative, high-quality supportive services to thousands, making it the largest agency dedicated to supporting LGBTQ homeless youths in the United States.

The Lesbian, Gay, Bisexual & Transgender Community Center empowers New York's LGBTQ communities to lead healthy, successful lives through advocacy; health and wellness programs; arts, entertainment, and cultural events; recovery, parenthood, and family support services.

Transgender Law Center is the largest national trans-led organization advocating for a world in which all people are free to define themselves and their futures through legal action and community-driven strategies to keep transgender and gender nonconforming people alive, thriving, and fighting for liberation.

Rainbow Railroad provides solutions for LGBTQI people who need immediate assistance because they are facing a serious threat to their lives and safety from state-sponsored violence.

Toronto's Sherbourne Health is committed to providing the LGBT community with transformative, high-quality primary care and chronic disease management services, health promotion and education, outreach and social support, and mental health services.

The YMCA of Greater Toronto's Sprott House, opened in 2007, provides transitional housing for up to 25 LGBTQ+ young people ages 16-24.